diff --git a/README.md b/README.md
index 7368ce1..7748946 100644
--- a/README.md
+++ b/README.md
@@ -205,6 +205,50 @@ specifying new width (`cols`) and height (`rows`).
 
 This command triggers `resize` event.
 
+#### mouse
+
+`mouse` command allows sending mouse events to the application running in the
+virtual terminal.
+
+```json
+{ "type": "mouse", "event": "click", "button": "left", "row": 10, "col": 25 }
+{ "type": "mouse", "event": "press", "button": "right", "row": 5, "col": 15, "control": true }
+{ "type": "mouse", "event": "drag", "button": "left", "row": 12, "col": 30 }
+{ "type": "mouse", "event": "release", "button": "left", "row": 12, "col": 30 }
+```
+
+Event types:
+- `press` - mouse button pressed down
+- `release` - mouse button released
+- `drag` - mouse motion while button is held down
+- `click` - convenience shorthand that sends both press and release events
+
+Supported buttons:
+- `left`, `middle`, `right` - standard mouse buttons
+- `wheel_up`, `wheel_down` - scroll wheel events
+
+Coordinates are 1-indexed, meaning row 1, col 1 represents the top-left cell of
+the terminal. Coordinates exceeding the current terminal size will trigger a
+warning but are still sent to the application.
+
+Optional modifier keys can be specified as boolean fields (default `false`):
+- `shift` - Shift key held during mouse event
+- `alt` - Alt/Option key held during mouse event
+- `control` - Control key held during mouse event
+
+Example with modifiers:
+```json
+{ "type": "mouse", "event": "click", "button": "left", "row": 10, "col": 25, "shift": true, "control": true }
+```
+
+**Important**: Mouse events use the SGR extended mouse protocol (`\x1b[<` format).
+The application running in the terminal must enable mouse tracking for these
+events to have any effect. Most modern TUI applications (vim with `:set mouse=a`,
+tmux, less, emacs, etc.) support mouse tracking and will enable it automatically
+when needed.
+
+This command doesn't trigger any event.
+
 ### WebSocket API
 
 The WebSocket API currently provides 2 endpoints:
diff --git a/src/api/stdio.rs b/src/api/stdio.rs
index 2aa2bf3..a50192a 100644
--- a/src/api/stdio.rs
+++ b/src/api/stdio.rs
@@ -24,6 +24,20 @@ struct ResizeArgs {
     rows: usize,
 }
 
+#[derive(Debug, Deserialize)]
+struct MouseArgs {
+    event: String,
+    button: String,
+    row: usize,
+    col: usize,
+    #[serde(default)]
+    shift: bool,
+    #[serde(default)]
+    alt: bool,
+    #[serde(default)]
+    control: bool,
+}
+
 pub async fn start(
     command_tx: mpsc::Sender<Command>,
     clients_tx: mpsc::Sender<session::Client>,
@@ -106,6 +120,55 @@ fn build_command(value: serde_json::Value) -> Result<Command, String> {
             Ok(Command::Input(seqs))
         }
 
+        Some("mouse") => {
+            let args: MouseArgs = args_from_json_value(value)?;
+
+            let is_click = args.event == "click";
+
+            let event_type = match args.event.as_str() {
+                "press" | "click" => command::MouseEventType::Press,
+                "release" => command::MouseEventType::Release,
+                "drag" => command::MouseEventType::Drag,
+                e => return Err(format!("invalid mouse event type: {}", e)),
+            };
+
+            let button = match args.button.as_str() {
+                "left" => command::MouseButton::Left,
+                "middle" => command::MouseButton::Middle,
+                "right" => command::MouseButton::Right,
+                "wheel_up" => command::MouseButton::WheelUp,
+                "wheel_down" => command::MouseButton::WheelDown,
+                b => return Err(format!("invalid mouse button: {}", b)),
+            };
+
+            // Validate coordinates (1-indexed)
+            if args.row == 0 || args.col == 0 {
+                return Err(
+                    "mouse coordinates must be 1-indexed (row >= 1, col >= 1)".to_string()
+                );
+            }
+
+            let modifiers = command::MouseModifiers {
+                shift: args.shift,
+                alt: args.alt,
+                control: args.control,
+            };
+
+            let mouse_event = command::MouseEvent {
+                event_type,
+                button,
+                row: args.row,
+                col: args.col,
+                modifiers,
+            };
+
+            if is_click {
+                Ok(Command::MouseClick(mouse_event))
+            } else {
+                Ok(Command::Mouse(mouse_event))
+            }
+        }
+
         Some("resize") => {
             let args: ResizeArgs = args_from_json_value(value)?;
             Ok(Command::Resize(args.cols, args.rows))
@@ -281,7 +344,7 @@ fn parse_key(key: String) -> InputSeq {
 #[cfg(test)]
 mod test {
     use super::{cursor_key, parse_line, standard_key, Command};
-    use crate::command::InputSeq;
+    use crate::command::{InputSeq, MouseButton, MouseEventType};
 
     #[test]
     fn parse_input() {
@@ -487,4 +550,140 @@ mod test {
     fn parse_invalid_json() {
         parse_line("{").expect_err("should fail");
     }
+
+    #[test]
+    fn parse_mouse_click() {
+        let command = parse_line(
+            r#"{ "type": "mouse", "event": "click", "button": "left", "row": 10, "col": 25 }"#,
+        )
+        .unwrap();
+        assert!(matches!(command, Command::MouseClick(_)));
+    }
+
+    #[test]
+    fn parse_mouse_press() {
+        let command = parse_line(
+            r#"{ "type": "mouse", "event": "press", "button": "right", "row": 5, "col": 15 }"#,
+        )
+        .unwrap();
+
+        if let Command::Mouse(event) = command {
+            assert!(matches!(event.event_type, MouseEventType::Press));
+            assert!(matches!(event.button, MouseButton::Right));
+            assert_eq!(event.row, 5);
+            assert_eq!(event.col, 15);
+            assert!(!event.modifiers.shift);
+            assert!(!event.modifiers.alt);
+            assert!(!event.modifiers.control);
+        } else {
+            panic!("expected Command::Mouse");
+        }
+    }
+
+    #[test]
+    fn parse_mouse_release() {
+        let command = parse_line(
+            r#"{ "type": "mouse", "event": "release", "button": "middle", "row": 1, "col": 1 }"#,
+        )
+        .unwrap();
+
+        if let Command::Mouse(event) = command {
+            assert!(matches!(event.event_type, MouseEventType::Release));
+            assert!(matches!(event.button, MouseButton::Middle));
+        } else {
+            panic!("expected Command::Mouse");
+        }
+    }
+
+    #[test]
+    fn parse_mouse_drag() {
+        let command = parse_line(
+            r#"{ "type": "mouse", "event": "drag", "button": "left", "row": 20, "col": 30 }"#,
+        )
+        .unwrap();
+
+        if let Command::Mouse(event) = command {
+            assert!(matches!(event.event_type, MouseEventType::Drag));
+        } else {
+            panic!("expected Command::Mouse");
+        }
+    }
+
+    #[test]
+    fn parse_mouse_with_modifiers() {
+        let command = parse_line(
+            r#"{ "type": "mouse", "event": "click", "button": "left", "row": 10, "col": 25, "shift": true, "control": true }"#,
+        )
+        .unwrap();
+
+        if let Command::MouseClick(event) = command {
+            assert!(event.modifiers.shift);
+            assert!(event.modifiers.control);
+            assert!(!event.modifiers.alt);
+        } else {
+            panic!("expected Command::MouseClick");
+        }
+    }
+
+    #[test]
+    fn parse_mouse_wheel() {
+        let command = parse_line(
+            r#"{ "type": "mouse", "event": "press", "button": "wheel_up", "row": 10, "col": 25 }"#,
+        )
+        .unwrap();
+
+        if let Command::Mouse(event) = command {
+            assert!(matches!(event.button, MouseButton::WheelUp));
+        } else {
+            panic!("expected Command::Mouse");
+        }
+
+        let command = parse_line(
+            r#"{ "type": "mouse", "event": "press", "button": "wheel_down", "row": 10, "col": 25 }"#,
+        )
+        .unwrap();
+
+        if let Command::Mouse(event) = command {
+            assert!(matches!(event.button, MouseButton::WheelDown));
+        } else {
+            panic!("expected Command::Mouse");
+        }
+    }
+
+    #[test]
+    fn parse_mouse_invalid_event() {
+        parse_line(
+            r#"{ "type": "mouse", "event": "invalid", "button": "left", "row": 10, "col": 25 }"#,
+        )
+        .expect_err("should fail");
+    }
+
+    #[test]
+    fn parse_mouse_invalid_button() {
+        parse_line(
+            r#"{ "type": "mouse", "event": "click", "button": "invalid", "row": 10, "col": 25 }"#,
+        )
+        .expect_err("should fail");
+    }
+
+    #[test]
+    fn parse_mouse_zero_row() {
+        parse_line(
+            r#"{ "type": "mouse", "event": "click", "button": "left", "row": 0, "col": 25 }"#,
+        )
+        .expect_err("should fail");
+    }
+
+    #[test]
+    fn parse_mouse_zero_col() {
+        parse_line(
+            r#"{ "type": "mouse", "event": "click", "button": "left", "row": 10, "col": 0 }"#,
+        )
+        .expect_err("should fail");
+    }
+
+    #[test]
+    fn parse_mouse_missing_args() {
+        parse_line(r#"{ "type": "mouse" }"#).expect_err("should fail");
+    }
 }
diff --git a/src/command.rs b/src/command.rs
index a9d29a7..8ed037b 100644
--- a/src/command.rs
+++ b/src/command.rs
@@ -1,6 +1,8 @@
 #[derive(Debug)]
 pub enum Command {
     Input(Vec<InputSeq>),
+    Mouse(MouseEvent),
+    MouseClick(MouseEvent), // Convenience: sends press then release
     Snapshot,
     Resize(usize, usize),
 }
@@ -28,3 +30,70 @@ fn seq_as_bytes(seq: &InputSeq, app_mode: bool) -> &[u8] {
         (InputSeq::Cursor(_seq1, seq2), true) => seq2.as_bytes(),
     }
 }
+
+#[derive(Debug, Clone)]
+pub struct MouseEvent {
+    pub event_type: MouseEventType,
+    pub button: MouseButton,
+    pub row: usize,
+    pub col: usize,
+    pub modifiers: MouseModifiers,
+}
+
+#[derive(Debug, Clone, PartialEq)]
+pub enum MouseEventType {
+    Press,
+    Release,
+    Drag,
+}
+
+#[derive(Debug, Clone, PartialEq)]
+pub enum MouseButton {
+    Left,
+    Middle,
+    Right,
+    WheelUp,
+    WheelDown,
+}
+
+#[derive(Debug, Clone, Default, PartialEq)]
+pub struct MouseModifiers {
+    pub shift: bool,
+    pub alt: bool,
+    pub control: bool,
+}
+
+pub fn mouse_to_bytes(event: &MouseEvent) -> Vec<u8> {
+    // Base button encoding per SGR protocol
+    let mut btn = match event.button {
+        MouseButton::Left => 0,
+        MouseButton::Middle => 1,
+        MouseButton::Right => 2,
+        MouseButton::WheelUp => 64,
+        MouseButton::WheelDown => 65,
+    };
+
+    // Add modifier bits
+    if event.modifiers.shift {
+        btn += 4;
+    }
+    if event.modifiers.alt {
+        btn += 8;
+    }
+    if event.modifiers.control {
+        btn += 16;
+    }
+
+    // Add motion bit for drag events
+    if matches!(event.event_type, MouseEventType::Drag) {
+        btn += 32;
+    }
+
+    // SGR format: ESC[<btn;col;rowM (press/drag) or m (release)
+    let suffix = match event.event_type {
+        MouseEventType::Press | MouseEventType::Drag => 'M',
+        MouseEventType::Release => 'm',
+    };
+
+    format!("\x1b[<{};{};{}{}", btn, event.col, event.row, suffix).into_bytes()
+}
diff --git a/src/main.rs b/src/main.rs
index e844e95..e1f043a 100644
--- a/src/main.rs
+++ b/src/main.rs
@@ -66,6 +66,16 @@ async fn start_http_api(
     Ok(())
 }
 
+fn validate_mouse_coordinates(mouse_event: &command::MouseEvent, session: &Session) {
+    let (cols, rows) = session.size();
+    if mouse_event.row > rows || mouse_event.col > cols {
+        eprintln!(
+            "warning: mouse coordinates ({},{}) exceed terminal size ({}x{})",
+            mouse_event.col, mouse_event.row, cols, rows
+        );
+    }
+}
+
 async fn run_event_loop(
     mut output_rx: mpsc::Receiver<Vec<u8>>,
     input_tx: mpsc::Sender<Vec<u8>>,
@@ -98,6 +108,28 @@ async fn run_event_loop(
                         input_tx.send(data).await?;
                     }
 
+                    Some(Command::Mouse(mouse_event)) => {
+                        validate_mouse_coordinates(&mouse_event, &session);
+                        let data = command::mouse_to_bytes(&mouse_event);
+                        input_tx.send(data).await?;
+                    }
+
+                    Some(Command::MouseClick(mouse_event)) => {
+                        validate_mouse_coordinates(&mouse_event, &session);
+
+                        // Send press event
+                        let mut press_event = mouse_event.clone();
+                        press_event.event_type = command::MouseEventType::Press;
+                        let press_data = command::mouse_to_bytes(&press_event);
+                        input_tx.send(press_data).await?;
+
+                        // Send release event
+                        let mut release_event = mouse_event;
+                        release_event.event_type = command::MouseEventType::Release;
+                        let release_data = command::mouse_to_bytes(&release_event);
+                        input_tx.send(release_data).await?;
+                    }
+
                     Some(Command::Snapshot) => {
                         session.snapshot();
                     }
diff --git a/src/session.rs b/src/session.rs
index 5dc59dd..01dfb14 100644
--- a/src/session.rs
+++ b/src/session.rs
@@ -76,6 +76,10 @@ impl Session {
         self.vt.cursor_key_app_mode()
     }
 
+    pub fn size(&self) -> (usize, usize) {
+        self.vt.size()
+    }
+
     pub fn subscribe(&self) -> Subscription {
         let (cols, rows) = self.vt.size();