diff --git a/projects/jupyter-server-ydoc/jupyter_server_ydoc/rooms.py b/projects/jupyter-server-ydoc/jupyter_server_ydoc/rooms.py
index 9cc45435..82f1fc73 100644
--- a/projects/jupyter-server-ydoc/jupyter_server_ydoc/rooms.py
+++ b/projects/jupyter-server-ydoc/jupyter_server_ydoc/rooms.py
@@ -247,6 +247,10 @@ def _on_document_change(self, target: str, event: Any) -> None:
             document. This tasks are debounced (60 seconds by default) so we
             need to cancel previous tasks before creating a new one.
         """
+        remove_duplicate_cells = getattr(self._document, "remove_duplicate_cells", None)
+        if target == "cells" and remove_duplicate_cells is not None:
+            asyncio.get_running_loop().call_soon(remove_duplicate_cells)
+
         # Collect autosave values from all clients
         autosave_states = [
             state.get("autosave", True)